Analysing Biological Assays 2011

Topics

• Data obtained from preliminary assays, optimal doses, realistic confidence limits and minimum and maximum doses
• How to differentiate and handle edge effects, hook effects and other dose effects
• Potency testing and how to measure nonparallelism
• The impact of different nonlinear and linear regression models particularly the 5 parameter, 4 parameter and 3 parameter logistic
• Guidelines for identifying and masking outliers
• Avoiding dilutional nonlinearity by compensating for different matrix effects
• Criteria for evaluating assays