Chromatography Fundamentals for Biologics Process Development explores the application of novel modeling and high throughput screening tools in chromatography process development, covering key separation modalities and workflows for both early and late-stage biologics.
Topics
- Different Preparative Chromatography Modalities and Operations
- Chromatographic Principles for Bioseparations
- Scale-Up and Scale-Down Principles for High Throughput Tools as well as General Scaling Practices from Process Development to GMP Manufacturing
- High Throughput Screening Techniques for Chromatography
- Examples of Modeling Approaches to Different Separation Challenges
- Mechanistic Models and their Application to Process Development
- Workflows and Strategies for Using Models and High Throughout Tools in Process Development, Including Considerations for Regulatory Filings
