FRPT (Flash Radiotherapy and Particle Therapy) 2025, Dec 2025

The FRPT (Flash Radiotherapy and Particle Therapy) 2025 is dedicated to the latest radiation therapies for oncology treatment.

Mechanisms
- Physico-Chemistry: FLASH chemistry, oxygen contribution, ROS
- Physics: modelling the FLASH effect, Geant 4 DNA, other code
- In vitro and in vivo studies
- Biology: molecular level, DNA damage, oxidative stress, inflammation; cellular level; tissue level
- Flash and drug / immune radiation combinations
Radiation Modalities
- Measurement of FLASH doses and dose rate for QA and real time measurement: ionisation chambers, film, solid state detectors, scintillators
- Radiation modalities: parameters for FLASH; Which conditions (radiation type, dose rate, dose per pulse, total irradiation time, biological end point) are optimal; Measurement of FLASH doses and dose rate for QA and real time measurement (how to guarantee the dose and prevent errors)
- Spatially fractionated radiotherapy, mini beams etc
- How: electrons, photons, protons; heavy ions: equipment involved, how beam is delivered, experimental end stations and set up
- New horizons Laser driven, VHEE
Flash in the Clinic
- TPS development for FLASH
- QA and dosimetry
- Clinical trial design and methodology, regulations
- Treatment regimen, fractionation, volume, combination
- Clinical trial: FLASH-IORT and superficial tumours; FLASH - proton; synchrotron trial; innovative trials
- Patient selection (how many patients might benefit from FLASH?), FLASH clinical workflow, health economics