Heart Failure: Mechanisms and Therapies is a conference dedicated to recent advances in HF treatment.
As life expectancy increases, individuals are experiencing the compounded effects of accumulated disease, genetic propensity, environmental stress, and behavior. The underpinnings of HF are multifactorial, providing a broad array of relevant biochemical therapeutic targets that could impact clinical symptoms and outcomes. Aging, the obesity epidemic and associated disorders, such as diabetes, have a major impact on heart failure pathophysiology. The roles of altered metabolism, mitochondrial dysfunction, protein quality control, inflammation, and fibrosis as well as the latest methods for single-cell analysis of subpopulations studies on epigenetic control of disease and heart development/regeneration will be featured.