8th International Conference Clinically Relevant Drug Transporters 2017

The 8th International Conference Clinically Relevant Drug Transporters 2017 is dedicated to the implementation of regulatory guidelines and the enhancement of innovative assessment strategies.

Topics

• Effective clinical translation of transporter-mediated PK and DDIs
• Drug development implications of the latest transporter recommendations from the FDA, EMA; PMDA and ITC
• Absolute quantification and differential expression of drug transporters
• Role of biomarkers in transporter- mediated efficacy, toxicity and DDI
• Quantitative transporter proteomics in translational DMPK
• New tools: Humanized mouse models, Pet-imaging, 3D-Models and organs-on-a-chip
• Importance of transport polymorphisms, as well as, ethnic, sex, and disease-state differences
• Optimizing transporter-mediated and/or - limited ADME