Modern Synthetic Organic Reactions

Modern Synthetic Organic Reactions is a course dedicated to recent developments and industrial opportunities.

Topics

• Photoredox catalysts- synthesis, properties and tuning
• Photoinduced electron transfer chemistry
• Aromatic C-H functionalisation
• Application and scale-up
• C-H coupling with halides and pseudohalides
• Aliphatic C-H functionalisation
• Oxidation with hypervalent iodine reagents
• C-H – C-H coupling
• C-C and C-X bond formation mediated by hypervalent reagents
• Rearrangements mediated by hypervalent iodine reagents
• Electrochemical redox processes
• Synthetic organic electrochemistry
• C-C and C-X bond formation via borrowing hydrogen
• Applications, setup and getting started
• Hydrogen mediated C-C bond formation (Krische chemistry)
• Using alcohols in place of halides and pseudohalides
• Catalyst classes and reaction examples
• Organocatalysis v’s transition metal processes
• Recent developments in biocatalysis
• Asymmetric transformations
• "Non-natural" reactions catalysed by modified enzymes
• Directed evolution of enzymes
• Base metals in cross coupling, hydrogenation and cyclization chemistry
• Green chemistry and sustainability
• New applications of base metals in industrial organic che

Who should Attend

• Process development chemists
• Discovery/Synthetic organic chemists
• Academics who wish to understand how industrial and process chemists view new synthetic chemistry and what can be done at the discovery stage to make the technology scalable
• Anyone wishing to learn more about essential new synthetic chemistry methodology and its potential application in an industrial setting