Practical Aspects of Small Molecule Drug Discovery 2016

Topics

• Target discovery and validation
• Project management and organisation of multi-disciplinary projects
• Fragment based drug discovery
• Hit discovery options
• Screening set selection, storage and quality control
• Phenotypic screening and mode of action elucidation
• Data mining
• Screening cascades, assay development and quality control
• Principles of compound optimisation and case histories
• Introduction to pharmacokinetics
• Intellectual property strategy
• In silico approaches to drug design
• An introduction to preclinical and clinical development
• Data packages required for out licensing and partnering